Breast Cancer - Female with a history of breast and colorectal carcinoma with a rising CEA for restaging

October 2004 History
58-year-old female for restaging of breast carcinoma.

October 2004 PET/CT Findings
This examination is compared to the patient’s previous exam of April 2004. When compared to the previous exam, there has been an interval improvement. Focal activity is again noted in the left sacrum, which has shown a slight decrease from the previous exam. There has been a significant decrease in activity within the lesion seen within the right iliac bone and right sacrum when compared to the previous exam. No definite activity is seen within the left inferior pubic ramus. There are areas of sclerosis seen throughout the chest, spine and pelvis. They are felt to be a few areas of mile activity within the thoracic spine, which may represent active disease. When compared to the previous exam, there has been not evidence of progression of disease. No focal pulmonary infiltrate of pleural effusion is identified.

October 2004 Impression
Continued improvement consistent with response to therapy. The most prominent area of activity is within the left sacrum, which has shown some decrease from previous exam. Small right pericardial lymph node with mile activity again noted. No evidence of progression of disease when compared to previous exam.

October 2004 Dosage
10.6 mCi FDG

April 2005 History
59-year-old female with a history of breast and colorectal carcinoma with a rising CEA for restaging.

April 2005 PET/CT Findings
This exam is compared to the patient’s previous study of October 2004. There is focal hypermetabolic activity seen with in the C5 vertebral body, the left sacrum and the left acetabulum. The area of activity within the left sacrum did appear to be present on the previous exam but shows increased activity. There is activity within the left superior pubic ramus. Linear areas of activity and sclerosis have developed within the anterior left fourth and fifth ribs. There is a focal area of activity in the right posterior sixth rib. There is an approximate 2-centimeter area of hypermetabolic activity with associated decreased attenuation seen with the liver, adjacent to the upper pole of the right kidney. There is also focal activity associated with a small approximate 1-centimeter nodule in the anteromedial right lung base. A tiny focus of activity is seen at the medial aspect of the left first rib. There is also an area of activity with associated sclerosis within the right iliac bone adjacent to the sacroiliac joint.

April 2005 Impression
There has been an interval progression of disease with new areas of hypermetabolic activity seen within the bones, particularly the ribs. New focus of activity within the liver, adjacent to the renal fossa and within the anteromedial right base.

April 2005 Dosage
9.89 mCi FDG

Courtesy of
Thompson Cancer Center